9,387 research outputs found

    Management of the Loco (Concholepas concholepas) as a Driver for Self-governance of Small-scale Benthic Fisheries in Chile

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    WRI led the "Reefs at Risk Revisited" analysis in collaboration with a broad partnership of more than 25 research, conservation, and educational organizations. Partners have provided data, offered guidance on the analytical approach, contributed to the report, and served as critical reviewers of the maps and findings.

    Introduction to a Special Issue on Inequality in the Workplace (“What Works?)

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    [Excerpt] While overt expressions of racial and gender bias in U.S. workplaces have declined markedly since the passage of the original Civil Rights Act and the creation of the Equal Employment Opportunity Commission a half century ago (Eagly and Chaiken 1993; Schuman, Steeh, Bobo, and Krysan 1997; Dobbin 2009), a steady stream of research indicates that powerful, if more covert forms of bias persist in contemporary workplaces (Greenwald and Banaji 1995; Pager, Western, and Bonikowski 2009; England 2010; Heilman 2012). In line with this research, high rates of individual and class-based lawsuits alleging racial and gender discrimination suggest that many employees perceive workplace discrimination to be an important, continuing employment problem (Hirsh 2009). Hence, to ensure workplace equity, prevent legal claims of discrimination, and/or rectify past and potential problems of bias, employers have implemented a growing array of organizational policies and practices aimed at reducing discrimination and increasing inclusion. Sometimes these efforts are voluntary; other times they are driven by specific mandates assigned to firms by courts as part of verdicts or settlements in cases involving charges of discrimination. Given the millions of dollars spent on making and monitoring such changes, surprisingly little evidence exists on the efficacy of various policies and practices adopted by organizations to address the problems and to capture the benefits of having a demographically diverse workforce. And even less evidence is available on the conditions that may moderate the impact of these policies and practices. Within the past decade, however, a limited but increasing body of research has focused on gauging how different practices associated with the label ‘‘diversity management’’ actually affect outcomes for women and minorities in organizations. The aim of this special issue is to bring together contemporary research that builds on this foundation in order to extend our understanding of the current variety of organizational arrangements that are intended to reduce bias and to promote more inclusive workplace

    Coherent nu-N scattering and the search for physics beyond the standard model

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    We focus in future proposals to measure coherent neutrino-nuclei scattering and we show that such kind of experiments are very sensitive to nonstandard neutrino interactions with quarks. First in a model independent parametrization and then we focused in particular models such as leptoquarks and models with extra neutral gauge bosons and with R-parity breaking interactions. We show that in all these three different types of new physics it is possible to obtain competitive bounds to those of future collider experiments. For the particular case of leptoquarks we found that the expected sensitivity to the coupling and mass for most of the future experimental setups is quite better than the current constraints.Comment: 6 pages, 1 Figure, Talk given at 11th Mexican Workshop on Particles and Fields 2007, Tuxtla Gutierrez, Mexico, 7-12 Nov 200

    Uncertainties in land use data

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    This paper deals with the description and assessment of uncertainties in land use data derived from Remote Sensing observations, in the context of hydrological studies. Land use is a categorical regionalised variable reporting the main socio-economic role each location has, where the role is inferred from the pattern of occupation of land. The properties of this pattern that are relevant to hydrological processes have to be known with some accuracy in order to obtain reliable results; hence, uncertainty in land use data may lead to uncertainty in model predictions. There are two main uncertainties surrounding land use data, positional and categorical. The first one is briefly addressed and the second one is explored in more depth, including the factors that influence it. We (1) argue that the conventional method used to assess categorical uncertainty, the confusion matrix, is insufficient to propagate uncertainty through distributed hydrologic models; (2) report some alternative methods to tackle this and other insufficiencies; (3) stress the role of metadata as a more reliable means to assess the degree of distrust with which these data should be used; and (4) suggest some practical recommendations

    Antiherpes simplex virus type 2 activity of the antimicrobial peptide subtilosin

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    In the present study we evaluated the antiviral activity of subtilosin, a cyclical peptide isolated from Bacillus amyloliquefaciens, against herpes simplex virus type 2 (HSV-2) in cell cultures and we investigated subtilosin mode of action. We determined, using a virus yield inhibition assay, that non cytotoxic concentrations of subtilosin inhibit HSV-2 replication in Vero cell cultures. Subtilosin strongly inhibited extracellular and total virus production even when it was added at 8 h post-infection indicating that not only virus release but also viral particle formation is impeded by the antiviral peptide. Although viral glycoprotein gD level of expression is not affected by the bacteriocin, an altered pattern of gD intracellular localization was detected by immunofluorescence assay in subtilosin treated culture. On the other hand, at high concentrations subtilosin displays virucidal action.Fil: Quintana, VerĂłnica Mara. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de QuĂ­mica BiolĂłgica. Laboratorio de VirologĂ­a; ArgentinaFil: Torres, NicolĂĄs. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de QuĂ­mica BiolĂłgica. Laboratorio de VirologĂ­a; Argentina. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas. Instituto de BiologĂ­a y Medicina Experimental. FundaciĂłn de Instituto de BiologĂ­a y Medicina Experimental. Instituto de BiologĂ­a y Medicina Experimental; ArgentinaFil: Wachsman, MĂłnica B.. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de QuĂ­mica BiolĂłgica. Laboratorio de VirologĂ­a; ArgentinaFil: Sinko, Patrick J.. State University of New Jersey; Estados UnidosFil: Castilla, Viviana. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de QuĂ­mica BiolĂłgica. Laboratorio de VirologĂ­a; ArgentinaFil: Chikindas, Michael. State University of New Jersey; Estados Unido

    Multipacting optimization of a 750 MHz rf dipole

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    Crab crossing schemes have been proposed to re-instate luminosity degradation due to crossing angles at the interaction points in next generation colliders to avoid the use of sharp bending magnets and their resulting large synchrotron radiation generation, highly undesirable in the detector region. The rf dipole has been considered for a different set of applications in several machines, both rings and linear colliders. We present in this paper a study of the effects on the multipacting levels and location depending on geometrical variations on the design for a crabbing/deflecting application in a high current (3/0.5 A), high repetition (750 MHz) electron/proton collider, as a matter to provide a comparison point for similar applications of rf dipoles

    Analysis of a 750 MHz SRF Dipole Cavity

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    There is a growing interest in using rf transverse deflecting structures for a plethora of applications in the current and future high performance colliders. In this paper, we present the results of a proof of principle superconducting rf dipole, designed as a prototype for a 750 MHz crabbing corrector for the Medium Energy Electron-Ion Collider (MEIC), which has been successfully tested at 4.2 K and 2 K at the Jefferson Lab’s Vertical Testing Area (VTA). The analysis of its rf performance during cryogenic testing, along with Helium pressure sensitivity, Lorentz detuning, surface resistance, and multipacting processing analysis are presented in this work. Detailed calculations of losses at the port flanges are included for completeness of the cavity’s cryogenic performance studies

    De Novo Generation of Infectious Prions In Vitro Produces a New Disease Phenotype

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    Prions are the proteinaceous infectious agents responsible for Transmissible Spongiform Encephalopathies. Compelling evidence supports the hypothesis that prions are composed exclusively of a misfolded version of the prion protein (PrPSc) that replicates in the body in the absence of nucleic acids by inducing the misfolding of the cellular prion protein (PrPC). The most common form of human prion disease is sporadic, which appears to have its origin in a low frequency event of spontaneous misfolding to generate the first PrPSc particle that then propagates as in the infectious form of the disease. The main goal of this study was to mimic an early event in the etiology of sporadic disease by attempting de novo generation of infectious PrPSc in vitro. For this purpose we analyzed in detail the possibility of spontaneous generation of PrPSc by the protein misfolding cyclic amplification (PMCA) procedure. Under standard PMCA conditions, and taking precautions to avoid cross-contamination, de novo generation of PrPSc was never observed, supporting the use of the technology for diagnostic applications. However, we report that PMCA can be modified to generate PrPSc in the absence of pre-existing PrPSc in different animal species at a low and variable rate. De novo generated PrPSc was infectious when inoculated into wild type hamsters, producing a new disease phenotype with unique clinical, neuropathological and biochemical features. Our results represent additional evidence in support of the prion hypothesis and provide a simple model to study the mechanism of sporadic prion disease. The findings also suggest that prion diversity is not restricted to those currently known, and that likely new forms of infectious protein foldings may be produced, resulting in novel disease phenotypes

    Mammalia, Chiroptera, Molossidae, <i>Molossops temminckii</i> (Burmeister, 1854), and Vespertilionidae, <i>Eptesicus furinalis</i> (dOrbigny and Gervais, 1847): New locality record and distribution extension in Cordoba Province, Argentina

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    During a field trip to the Ramsar site “Bañados del RĂ­o Dulce y Laguna Mar Chiquita” we captured three specimensof Molossops temminckii (Burmeister, 1854) and two of Eptesicus furinalis (d’Orbigny and Gervais, 1847). Molossopstemminckii has a wide distribution in Argentina, but this new record represents the second mention of the species for theCordoba Province after 13 years. The specimens of E. furinalis represent the tenth record for Cordoba and the second for RĂ­oPrimero Department. This new information reflects the scarcity of systematic studies on bats in Cordoba Province
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